Document Type

Article

Keywords

Crystal structures, Bis(8-quinolinolato)copper(II) complexes, Bis(7-fluoro-8-quinolinolato) copper(II), Bis(2-methyl-7-nitro-8-quinolinolato)copper(II), Bis(2-methyl-8-quinolinolato)copper( II)

Disciplines

Biochemistry

Abstract

A hypothesis that the geometry of a potential fungicide must be consistent with that of the pores of the fungal spore wall in order to penetrate it and be toxic has been developed. Certain bis(8-quinolinolato)copper(II) complexes seemed to contradict this. To resolve this issue, structures of bis(7-fluoro-8-quinolinolato )copper(II) (1), bis(2-methyl-8-quinolinolato )copper(II) (2), and bis(2-methyl-7-nitro-8-quinolinolato)copper(II) (3) were solved. The ligands of 1 are square planar with copper at the center of symmetry. In 2 and 3 the methyl group at C2 interacts with the other 8- quinolinol ligand, producing a significant distortion of the square planar geometry which causes a rotation about the N-Cu-N axis and allows the molecules to be polar, more compact, and manifest their toxicity. Bis(7-Nitro-8-quino1inolato)copper(II) is square planar and nontoxic

Article Number

1055

Publication Date

1998

Comments

Monatshefte für chemie 129:843-853. http://dx.doi.org/10.1007/PL00013492

Included in

Biochemistry Commons

Share

COinS